TTF I. Addition of dimethyl acetylenedicarboxylate to ethylene trithiocarbonate; Dimethyl 1,3-dithiole-2-thione-4,5-dicarboxylate
SyntheticPage 277
DOI:
10.1039/SP277
Submitted Jun 05, 2008, published Jun 05, 2008
Chemicals Used
ethylene trithiocarbonate (Aldrich),
dimethyl acetylenedicarboxylate (Aldrich)
Procedure
Dimethyl acetylenedicarboxylate (10.4 g, 0.073 mol) and ethylene trithiocarbonate (10 g, 0.073 mol) were dissolved in toluene (25 ml). Mixture was refluxed overnight at 150°C. Product precipitated upon cooling (water/ice bath), filtered without washing, dried in vacuo (Yield 16.8g). Concentration of the filtrate gave second crop (Yield 2.4g) Overall yield (19.2g, 89%)
Author's Comments
Has been performed several times with similar yields. Product used immediately in subsequent reaction.
Data
1H NMR (400MHz, Acetone-d6, 298K) 3.91 (s, CH3)
Lead Reference
L.R. Melby, H.D. Hartzler, W.A. Sheppard, J.Org. Chem. Vol. 39, No. 16, (1974) 2456-2458
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Keywords: tetrathiafulvalene, TTF, addition, alkynes, esters, heterocyclic compounds, sulphides